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Cellular resolution maps of X-chromosome inactivation: implications for neural development, function, and disease
Female eutherian mammals use X-chromosome inactivation (XCI) to epigenetically regulate gene expression from ~4% of genes. To quantitatively map the topography of XCI for defined cell types at single cell resolution, we have generated female mice that carry X-linked, Cre-activated, and nuclear-local...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3950970/ https://ncbi.nlm.nih.gov/pubmed/24411735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.10.051 |
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