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The activation domain of a basic helix-loop-helix protein is masked by repressor interaction with domains distinct from that required for transcription regulation.

While there are many examples of protein-protein interactions modulating the DNA-binding activity of transcription factors, little is known of the molecular mechanisms underlying the regulation of the transcription activation function. Using a two-hybrid system we show here that transcription repres...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:EMBO J
Päätekijät: Jayaraman, P S, Hirst, K, Goding, C R
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 1994
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395073/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8187772/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06496.x
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