Loading...

Mediation of NGF signaling by post-translational inhibition of HES-1, a basic helix–loop–helix repressor of neuronal differentiation

The induction of neurite outgrowth by NGF is a transcription-dependent process in PC12 cells, but the transcription factors that mediate this process are not known. Here we show that the bHLH transcriptional repressor HES-1 is a mediator of this process. Inactivation of endogenous HES-1 by forced ex...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Ström, Anders, Castella, Paul, Rockwood, Julia, Wagner, John, Caudy, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC316755/
https://ncbi.nlm.nih.gov/pubmed/9389649
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!