FeON-FeOFF: the Helicobacter pylori Fur regulator commutates iron-responsive transcription by discriminative readout of opposed DNA grooves

Most transcriptional regulators bind nucleotide motifs in the major groove, although some are able to recognize molecular determinants conferred by the minor groove of DNA. Here we report a transcriptional commutator switch that exploits the alternative readout of grooves to mediate opposite output...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Agriesti, Francesca, Roncarati, Davide, Musiani, Francesco, Del Campo, Cristian, Iurlaro, Mario, Sparla, Francesca, Ciurli, Stefano, Danielli, Alberto, Scarlato, Vincenzo
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950669/
https://ncbi.nlm.nih.gov/pubmed/24322295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1258
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky