FeON-FeOFF: the Helicobacter pylori Fur regulator commutates iron-responsive transcription by discriminative readout of opposed DNA grooves

Most transcriptional regulators bind nucleotide motifs in the major groove, although some are able to recognize molecular determinants conferred by the minor groove of DNA. Here we report a transcriptional commutator switch that exploits the alternative readout of grooves to mediate opposite output...

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Autori principali: Agriesti, Francesca, Roncarati, Davide, Musiani, Francesco, Del Campo, Cristian, Iurlaro, Mario, Sparla, Francesca, Ciurli, Stefano, Danielli, Alberto, Scarlato, Vincenzo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950669/
https://ncbi.nlm.nih.gov/pubmed/24322295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1258
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