Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene.

Cyclin D1 is the regulatory subunit of certain protein kinases thought to advance the G1 phase of the cell cycle. Deregulated cyclin D1 expression has been implicated in several human neoplasms, most consistently in centrocytic B lymphoma, where the cyclin D1 gene usually has been translocated to an...

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Bibliographic Details
Main Authors: Bodrug, S E, Warner, B J, Bath, M L, Lindeman, G J, Harris, A W, Adams, J M
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC395065/
https://ncbi.nlm.nih.gov/pubmed/8187765
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