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Development and validation of a dried blood spot assay for the quantification of ribavirin using liquid chromatography coupled to mass spectrometry

Efficient, inexpensive and sensitive assays for the measurement of drugs are of interest for pharmacokinetic and pharmacodynamics (PK-PD) analysis. Dried blood spots (DBS) are a unique bioanaltyical matrix with the potential to fulfill this interest for the measurement of numerous analytes. Here we...

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Autores principales: Jimmerson, Leah C., Zheng, Jia-Hua, Bushman, Lane R., MacBrayne, Christine E., Anderson, Peter L., Kiser, Jennifer J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950646/
https://ncbi.nlm.nih.gov/pubmed/24291608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2013.10.035
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