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A temporal requirement for Hippo signaling in mammary gland differentiation, growth, and tumorigenesis

Despite recent progress, the physiological role of Hippo signaling in mammary gland development and tumorigenesis remains poorly understood. Here we show that the Hippo pathway is functionally dispensable in virgin mammary glands but specifically required during pregnancy. In contrast to many other...

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Detalhes bibliográficos
Main Authors: Chen, Qian, Zhang, Nailing, Gray, Ryan S., Li, Huili, Ewald, Andrew J., Zahnow, Cynthia A., Pan, Duojia
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950341/
https://ncbi.nlm.nih.gov/pubmed/24589775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.233676.113
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