The CD45 tyrosine phosphatase regulates specific pools of antigen receptor-associated p59fyn and CD4-associated p56lck tyrosine in human T-cells.

A newly isolated T-cell line (CB1) derived from a T-acute lymphoblastic leukaemia (T-ALL) patient contained cells (40% of total) which did not express the CD45 phosphotyrosine phosphatase. The cells were sorted into CD45- and CD45+ populations and shown to be clonal in origin. T-cell receptor (TCR)...

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Pubblicato in:	EMBO J
Autori principali:	Biffen, M, McMichael-Phillips, D, Larson, T, Venkitaraman, A, Alexander, D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395033/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8168490/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06461.x
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