Analysis of Ig-alpha-tyrosine kinase interaction reveals two levels of binding specificity and tyrosine phosphorylated Ig-alpha stimulation of Fyn activity.

The B cell antigen receptor complex (BCR) is composed of membrane Ig and heterodimers of Ig-alpha and Ig-beta/gamma. Recent findings indicate that Ig-alpha associates with Src-family kinases, including Fyn and Lyn, via an approximately 26 amino acid motif termed ARH1. Studies reported here (i) defin...

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Pubblicato in:	EMBO J
Autori principali:	Clark, M R, Johnson, S A, Cambier, J C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395032/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8168489/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06460.x
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