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Mapping the p53 transcriptome universe using p53 natural polymorphs

The tumor suppressor p53 has defined roles in varied cellular processes including apoptosis and DNA repair. While conventional genomic approaches have suggested a large number of p53 targets, there is a need for a systematic approach to validate these putative genes. We developed a method to identif...

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Detalhes bibliográficos
Main Authors: Wang, B, Niu, D, Lam, T H, Xiao, Z, Ren, E C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950315/
https://ncbi.nlm.nih.gov/pubmed/24076587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.132
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