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Telmisartan ameliorates glutamate-induced neurotoxicity: roles of AT(1) receptor blockade and PPARγ activation

Sartans (Angiotensin II AT(1) Receptor Blockers, ARBs) are powerful neuroprotective agents in vivo and protect against IL-1β neurotoxicity in vitro. The purpose of this research was to determine the extent of sartan neuroprotection against glutamate excitotoxicity, a common cause of neuronal injury...

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Detalhes bibliográficos
Main Authors: Wang, Juan, Pang, Tao, Hafko, Roman, Benicky, Julius, Sanchez-Lemus, Enrique, Saavedra, Juan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950310/
https://ncbi.nlm.nih.gov/pubmed/24316465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.11.022
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