Brain Endothelial Cells Control Fertility through Ovarian-Steroid–Dependent Release of Semaphorin 3A

Neuropilin-1 (Nrp1) guides the development of the nervous and vascular systems, but its role in the mature brain remains to be explored. Here we report that the expression of the 65 kDa isoform of Sema3A, the ligand of Nrp1, by adult vascular endothelial cells, is regulated during the ovarian cycle...

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Autors principals: Giacobini, Paolo, Parkash, Jyoti, Campagne, Céline, Messina, Andrea, Casoni, Filippo, Vanacker, Charlotte, Langlet, Fanny, Hobo, Barbara, Cagnoni, Gabriella, Gallet, Sarah, Hanchate, Naresh Kumar, Mazur, Danièle, Taniguchi, Masahiko, Mazzone, Massimiliano, Verhaagen, Joost, Ciofi, Philippe, Bouret, Sébastien G., Tamagnone, Luca, Prevot, Vincent
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949669/
https://ncbi.nlm.nih.gov/pubmed/24618750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001808
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