Brain Endothelial Cells Control Fertility through Ovarian-Steroid–Dependent Release of Semaphorin 3A

Neuropilin-1 (Nrp1) guides the development of the nervous and vascular systems, but its role in the mature brain remains to be explored. Here we report that the expression of the 65 kDa isoform of Sema3A, the ligand of Nrp1, by adult vascular endothelial cells, is regulated during the ovarian cycle...

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Detalhes bibliográficos
Main Authors: Giacobini, Paolo, Parkash, Jyoti, Campagne, Céline, Messina, Andrea, Casoni, Filippo, Vanacker, Charlotte, Langlet, Fanny, Hobo, Barbara, Cagnoni, Gabriella, Gallet, Sarah, Hanchate, Naresh Kumar, Mazur, Danièle, Taniguchi, Masahiko, Mazzone, Massimiliano, Verhaagen, Joost, Ciofi, Philippe, Bouret, Sébastien G., Tamagnone, Luca, Prevot, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949669/
https://ncbi.nlm.nih.gov/pubmed/24618750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001808
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