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Sertraline inhibits the transport of PAT1 substrates in vivo and in vitro
BACKGROUND AND PURPOSE: Intestinal nutrient transporters may mediate the uptake of drugs. The aim of this study was to investigate whether sertraline interacts with the intestinal proton-coupled amino acid transporter 1 PAT1 (SLC36A1). EXPERIMENTAL APPROACH: In vitro investigations of interactions b...
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| Glavni autori: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Publishing Ltd
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949652/ https://ncbi.nlm.nih.gov/pubmed/23962042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12341 |
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