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Impaired removal of Vβ8(+) lymphocytes aggravates colitis in mice deficient for B cell lymphoma-2-interacting mediator of cell death (Bim)
We investigated the role of B cell lymphoma (BCL)-2-interacting mediator of cell death (Bim) for lymphocyte homeostasis in intestinal mucosa. Lymphocytes lacking Bim are refractory to apoptosis. Chronic colitis was induced in Bim-deficient mice (Bim(–/–)) with dextran sulphate sodium (DSS). Weight l...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Science Inc
2013
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949637/ https://ncbi.nlm.nih.gov/pubmed/23668821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12137 |
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