Dimerization interfaces formed between the DNA binding domains determine the cooperative binding of RXR/RAR and RXR/TR heterodimers to DR5 and DR4 elements.

We have previously reported that the binding site repertoires of heterodimers formed between retinoid X receptor (RXR) and either retinoic acid receptor (RAR) or thyroid hormone receptor (TR) bound to response elements consisting of directly repeated PuG(G/T)TCA motifs spaced by 1-5 bp [direct repea...

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Vydáno v:	EMBO J
Hlavní autoři:	Zechel, C, Shen, X Q, Chambon, P, Gronemeyer, H
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Publishing Group 1994
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394959/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8137825/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06395.x
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