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Expression of LIF in transgenic mice results in altered thymic epithelium and apparent interconversion of thymic and lymph node morphologies.

Leukemia inhibitory factor (LIF) is a cytokine involved in embryonic and hematopoietic development. To investigate the effects of LIF on the lymphoid system, we generated a line of transgenic mice that expresses diffusible LIF protein specifically in T cells. These mice display two categories of phe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shen, M M, Skoda, R C, Cardiff, R D, Campos-Torres, J, Leder, P, Ornitz, D M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC394955/
https://ncbi.nlm.nih.gov/pubmed/8137821
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