Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease.

Overexpression and amplification of the neu (c-erbB2, ERBB2) protooncogene have been implicated in the development of aggressive human breast cancer. To directly assess the effect of mammary gland-specific expression of the neu protooncogene, transgenic mice carrying unactivated neu under the transc...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Guy, C T, Webster, M A, Schaller, M, Parsons, T J, Cardiff, R D, Muller, W J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50384/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1359541/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.22.10578
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