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Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease.

Overexpression and amplification of the neu (c-erbB2, ERBB2) protooncogene have been implicated in the development of aggressive human breast cancer. To directly assess the effect of mammary gland-specific expression of the neu protooncogene, transgenic mice carrying unactivated neu under the transc...

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Bibliografiske detaljer
Main Authors: Guy, C T, Webster, M A, Schaller, M, Parsons, T J, Cardiff, R D, Muller, W J
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC50384/
https://ncbi.nlm.nih.gov/pubmed/1359541
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