Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal.

Overexpression of wild-type p53 in p53-deficient leukemic cells induces apoptosis, which can be inhibited by hematopoietic survival factors. This suggests that p53 may contribute to survival factor dependence. To assess the role of wild-type p53 in mediating apoptosis following survival factor withd...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Gottlieb, E, Haffner, R, von Rüden, T, Wagner, E F, Oren, M
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC394954/
https://ncbi.nlm.nih.gov/pubmed/8137820
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki