Mechanism of fibroblast inflammatory responses to Pseudomonas aeruginosa elastase

Receptor tyrosine kinases, including the epidermal growth factor receptors (EGFR), are able to activate the mitogen-activated protein kinases (MAPK) via several adaptor proteins and protein kinases such as Raf. EGFR can be activated by a variety of extracellular stimuli including neutrophil elastase...

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Bibliographic Details
Main Authors: Azghani, Ali O., Neal, Kourtney, Idell, Steven, Amaro, Rodolfo, Baker, Jason W., Omri, Abdelwahab, Pendurthi, Usha R.
Format: Artigo
Language:Inglês
Published: Society for General Microbiology 2014
Subjects:
Microbial Pathogenicity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949346/
https://ncbi.nlm.nih.gov/pubmed/24385476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.075325-0
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