Nitric Oxide Inhibits Hetero-adhesion of Cancer Cells to Endothelial Cells: Restraining Circulating Tumor Cells from Initiating Metastatic Cascade

Adhesion of circulating tumor cells (CTCs) to vascular endothelial bed becomes a crucial starting point in metastatic cascade. We hypothesized that nitric oxide (NO) may prevent cancer metastasis from happening by its direct vasodilation and inhibition of cell adhesion molecules (CAMs). Here we show...

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Detalhes bibliográficos
Main Authors: Lu, Yusheng, Yu, Ting, Liang, Haiyan, Wang, Jichuang, Xie, Jingjing, Shao, Jingwei, Gao, Yu, Yu, Suhong, Chen, Shuming, Wang, Lie, Jia, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949248/
https://ncbi.nlm.nih.gov/pubmed/24614329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04344
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