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Cell cycle-dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein.

Accumulation of the amyloid A beta peptide, which is derived from a larger precursor protein (APP), and the formation of plaques, are major events believed to be involved in the etiology of Alzheimer's disease. Abnormal regulation of the metabolism of APP may contribute to the deposition of pla...

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Autors principals: Suzuki, T, Oishi, M, Marshak, D R, Czernik, A J, Nairn, A C, Greengard, P
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC394920/
https://ncbi.nlm.nih.gov/pubmed/8131745
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