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Drug-induced reduction in estimated glomerular filtration rate in patients with ALK-positive non-small cell lung cancer treated with the ALK-inhibitor crizotinib

BACKGROUND: Renal side effects of crizotinib have not been investigated previously. METHODS: Estimated Glomerular Filtration Rate (eGFR) was calculated using the CKD-EPI creatinine-based prediction equation during the first 12 weeks of crizotinib and post-crizotinib prior to the introduction of any...

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Autori principali: Brosnan, Evelyn M., Weickhardt, Andrew J., Lu, Xian, Maxon, Delee A, Barón, Anna E., Chonchol, Michel, Camidge, D. Ross
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949169/
https://ncbi.nlm.nih.gov/pubmed/24258622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28478
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