The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion.

Nuclear bodies (NBs) are ultrastructurally defined granules predominantly found in dividing cells. Here we show that PML, a protein involved in the t(15;17) translocation of acute promyelocytic leukaemia (APL), is specifically bound to a NB. PML and several NB-associated proteins, found as auto-anti...

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Detalhes bibliográficos
Main Authors: Koken, M H, Puvion-Dutilleul, F, Guillemin, M C, Viron, A, Linares-Cruz, G, Stuurman, N, de Jong, L, Szostecki, C, Calvo, F, Chomienne, C
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC394915/
https://ncbi.nlm.nih.gov/pubmed/8131741
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