Skeletal muscle microvascular oxygenation dynamics in heart failure: exercise training and nitric oxide-mediated function

Chronic heart failure (CHF) impairs nitric oxide (NO)-mediated regulation of skeletal muscle O(2) delivery-utilization matching such that microvascular oxygenation falls faster (i.e., speeds PO(2)mv kinetics) during increases in metabolic demand. Conversely, exercise training improves (slows) muscle...

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Bibliographic Details
Main Authors: Hirai, Daniel M., Copp, Steven W., Holdsworth, Clark T., Ferguson, Scott K., McCullough, Danielle J., Behnke, Bradley J., Musch, Timothy I., Poole, David C.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2014
Subjects:
Vascular Biology and Microcirculation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949066/
https://ncbi.nlm.nih.gov/pubmed/24414070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00901.2013
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