Effects of chronic heart failure on neuronal nitric oxide synthase-mediated control of microvascular O(2) pressure in contracting rat skeletal muscle

Chronic heart failure (CHF) impairs nitric oxide (NO)-mediated regulation of the skeletal muscle microvascular O(2) delivery/[Image: see text] ratio (which sets the microvascular O(2) pressure, [Image: see text]). Given the pervasiveness of endothelial dysfunction in CHF, this NO-mediated dysregulat...

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Autores principales: Copp, Steven W, Hirai, Daniel M, Ferguson, Scott K, Holdsworth, Clark T, Musch, Timothy I, Poole, David C
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2012
Materias:
Skeletal Muscle and Exercise
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547272/
https://ncbi.nlm.nih.gov/pubmed/22687613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.235929
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