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Protein kinase G increases antioxidant function in lung microvascular endothelial cells by inhibiting the c-Abl tyrosine kinase
Oxidant injury contributes to acute lung injury (ALI). We previously reported that activation of protein kinase G(I) (PKG(I)) posttranscriptionally increased the key antioxidant enzymes catalase and glutathione peroxidase 1 (Gpx-1) and attenuated oxidant-induced cytotoxicity in mouse lung microvascu...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3948974/ https://ncbi.nlm.nih.gov/pubmed/24401847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00375.2012 |
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