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miR-23a is decreased during muscle atrophy by a mechanism that includes calcineurin signaling and exosome-mediated export
Skeletal muscle atrophy is prevalent in chronic diseases, and microRNAs (miRs) may play a key role in the wasting process. miR-23a was previously shown to inhibit the expression of atrogin-1 and muscle RING-finger protein-1 (MuRF1) in muscle. It also was reported to be regulated by cytoplasmic nucle...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3948973/ https://ncbi.nlm.nih.gov/pubmed/24336651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00266.2013 |
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