Docosahexaenoic acid prevents palmitate-induced activation of proteolytic systems in C2C12 myotubes

Saturated fatty acids like palmitate contribute to muscle atrophy in a number of conditions (e.g., Type II diabetes) by altering insulin signaling. Akt is a key modulator of protein balance that inhibits the FoxO transcription factors (e.g., FoxO3) which selectively induce the expression of atrophy-...

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Hlavní autoři: Woodworth-Hobbs, Myra E., Hudson, Matthew B., Rahnert, Jill A., Zheng, Bin, Franch, Harold A., Price, S. Russ
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118671/
https://ncbi.nlm.nih.gov/pubmed/24835079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2014.03.017
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