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Docosahexaenoic acid prevents palmitate-induced activation of proteolytic systems in C2C12 myotubes
Saturated fatty acids like palmitate contribute to muscle atrophy in a number of conditions (e.g., Type II diabetes) by altering insulin signaling. Akt is a key modulator of protein balance that inhibits the FoxO transcription factors (e.g., FoxO3) which selectively induce the expression of atrophy-...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4118671/ https://ncbi.nlm.nih.gov/pubmed/24835079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2014.03.017 |
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