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CaMKII Mediates Recruitment and Activation of the Deubiquitinase CYLD at the Postsynaptic Density

NMDA treatment of cultured hippocampal neurons causes recruitment of CYLD, as well as CaMKII, to the postsynaptic density (PSD), as shown by immunoelectron microscopy. Recruitment of CYLD, a deubiquitinase specific for K63-linked polyubiquitins, is blocked by pre-treatment with tatCN21, a CaMKII inh...

詳細記述

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書誌詳細
主要な著者: Thein, Soe, Tao-Cheng, Jung-Hwa, Li, Yan, Bayer, K. Ulrich, Reese, Thomas S., Dosemeci, Ayse
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948843/
https://ncbi.nlm.nih.gov/pubmed/24614225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091312
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