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CaMKII Mediates Recruitment and Activation of the Deubiquitinase CYLD at the Postsynaptic Density

NMDA treatment of cultured hippocampal neurons causes recruitment of CYLD, as well as CaMKII, to the postsynaptic density (PSD), as shown by immunoelectron microscopy. Recruitment of CYLD, a deubiquitinase specific for K63-linked polyubiquitins, is blocked by pre-treatment with tatCN21, a CaMKII inh...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Thein, Soe, Tao-Cheng, Jung-Hwa, Li, Yan, Bayer, K. Ulrich, Reese, Thomas S., Dosemeci, Ayse
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948843/
https://ncbi.nlm.nih.gov/pubmed/24614225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091312
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