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CaMKII Mediates Recruitment and Activation of the Deubiquitinase CYLD at the Postsynaptic Density

NMDA treatment of cultured hippocampal neurons causes recruitment of CYLD, as well as CaMKII, to the postsynaptic density (PSD), as shown by immunoelectron microscopy. Recruitment of CYLD, a deubiquitinase specific for K63-linked polyubiquitins, is blocked by pre-treatment with tatCN21, a CaMKII inh...

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Autori principali: Thein, Soe, Tao-Cheng, Jung-Hwa, Li, Yan, Bayer, K. Ulrich, Reese, Thomas S., Dosemeci, Ayse
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948843/
https://ncbi.nlm.nih.gov/pubmed/24614225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091312
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