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Association of p56lck with the cytoplasmic domain of CD4 modulates HIV-1 expression.

To investigate the role played by the cytoplasmic domain of the CD4 glycoprotein in the process of HIV infection, we have transfected two CD4-negative human T cell lines with cDNAs encoding the full-length CD4 and a truncated form of the molecule, lacking most of the cytoplasmic domain. Levels of vi...

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Autors principals: Tremblay, M, Meloche, S, Gratton, S, Wainberg, M A, Sékaly, R P
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC394876/
https://ncbi.nlm.nih.gov/pubmed/8112293
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