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The Antidepressant Agomelatine Improves Memory Deterioration and Upregulates CREB and BDNF Gene Expression Levels in Unpredictable Chronic Mild Stress (UCMS)-Exposed Mice
Agomelatine, a novel antidepressant with established clinical efficacy, acts as an agonist of melatonergic MT(1) and MT(2) receptors and as an antagonist of 5-HT(2C) receptors. The present study was undertaken to investigate whether chronic treatment with agomelatine would block unpredictable chroni...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Libertas Academica
2014
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3948735/ https://ncbi.nlm.nih.gov/pubmed/24634580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/DTI.S13870 |
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