The DUSP26 phosphatase activator adenylate kinase 2 regulates FADD phosphorylation and cell growth

Adenylate kinase 2 (AK2), which balances adenine nucleotide pool, is a multi-functional protein. Here we show that AK2 negatively regulates tumour cell growth. AK2 forms a complex with dual-specificity phosphatase 26 (DUSP26) phosphatase and stimulates DUSP26 activity independently of its AK activit...

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Detalhes bibliográficos
Main Authors: Kim, Hyunjoo, Lee, Ho-June, Oh, Yumin, Choi, Seon-Guk, Hong, Se-Hoon, Kim, Hyo-Jin, Lee, Song-Yi, Choi, Ji-Woo, Su Hwang, Deog, Kim, Key-Sun, Kim, Hyo-Joon, Zhang, Jianke, Youn, Hyun-Jo, Noh, Dong-Young, Jung, Yong-Keun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948464/
https://ncbi.nlm.nih.gov/pubmed/24548998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4351
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