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Evolution of the Retroviral Restriction Gene Fv1: Inhibition of Non-MLV Retroviruses

Fv1 is the prototypic restriction factor that protects against infection by the murine leukemia virus (MLV). It was first identified in cells that were derived from laboratory mice and was found to be homologous to the gag gene of an endogenous retrovirus (ERV). To understand the evolution of the ho...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yap, Melvyn W., Colbeck, Emily, Ellis, Scott A., Stoye, Jonathan P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948346/
https://ncbi.nlm.nih.gov/pubmed/24603659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003968
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