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Evolution of the Retroviral Restriction Gene Fv1: Inhibition of Non-MLV Retroviruses

Fv1 is the prototypic restriction factor that protects against infection by the murine leukemia virus (MLV). It was first identified in cells that were derived from laboratory mice and was found to be homologous to the gag gene of an endogenous retrovirus (ERV). To understand the evolution of the ho...

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Détails bibliographiques
Auteurs principaux: Yap, Melvyn W., Colbeck, Emily, Ellis, Scott A., Stoye, Jonathan P.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948346/
https://ncbi.nlm.nih.gov/pubmed/24603659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003968
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