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Evolution of the Retroviral Restriction Gene Fv1: Inhibition of Non-MLV Retroviruses

Fv1 is the prototypic restriction factor that protects against infection by the murine leukemia virus (MLV). It was first identified in cells that were derived from laboratory mice and was found to be homologous to the gag gene of an endogenous retrovirus (ERV). To understand the evolution of the ho...

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Detalhes bibliográficos
Main Authors: Yap, Melvyn W., Colbeck, Emily, Ellis, Scott A., Stoye, Jonathan P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948346/
https://ncbi.nlm.nih.gov/pubmed/24603659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003968
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