Local immunostimulation leading to rejection of accepted male skin grafts by female mice as a model for cancer immunotherapy

Female mice of inbred strain CBA do not reject syngeneic male skin grafts even though they mount a T-cell response against the male-specific HY antigen. We show that local immunostimulation performed by injecting cytokines and Toll-like receptor ligands in close vicinity to the graft causes rejectio...

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Main Authors: Bourdeaux, Christophe, Lurquin, Christophe, Jacquemart, Isabelle, Lethé, Bernard, Brasseur, Francis, van Baren, Nicolas, Baurain, Jean-François, Dyson, Julian, Van Snick, Jacques, Uyttenhove, Catherine, Boon, Thierry
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948291/
https://ncbi.nlm.nih.gov/pubmed/24550491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401115111
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