Central role for hydrogen peroxide in P2Y1 ADP receptor-mediated cellular responses in vascular endothelium

ADP activates a family of cell surface receptors that modulate signaling pathways in a broad range of cells. ADP receptor antagonists are widely used to treat cardiovascular disease states. These studies identify a critical role for the stable reactive oxygen species hydrogen peroxide (H(2)O(2)) in...

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Bibliographische Detailangaben
Hauptverfasser: Kalwa, Hermann, Sartoretto, Juliano L., Martinelli, Roberta, Romero, Natalia, Steinhorn, Benjamin S., Tao, Ming, Ozaki, C. Keith, Carman, Christopher V., Michel, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948230/
https://ncbi.nlm.nih.gov/pubmed/24550450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320854111
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