The Influence of Polygenic Risk Scores on Heritability of Anti-CCP Level in RA

OBJECTIVE: To study genetic factors that influence quantitative anti-cyclic citrullinated peptide (anti-CCP) antibody levels in RA patients. METHODS: We carried out a genome wide association study (GWAS) meta-analysis using 1,975 anti-CCP+ RA patients from 3 large cohorts, the Brigham Rheumatoid Art...

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Detalhes bibliográficos
Main Authors: Cui, Jing, Taylor, Kimberly E., Lee, Yvonne C., Källberg, Henrik, Weinblatt, Michael E., Coblyn, Jonathan S., Klareskog, Lars, Criswell, Lindsey A., Gregersen, Peter K., Shadick, Nancy A., Plenge, Robert M., Karlson, Elizabeth W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948067/
https://ncbi.nlm.nih.gov/pubmed/24385024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2013.68
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