The Influence of Polygenic Risk Scores on Heritability of Anti-CCP Level in RA

OBJECTIVE: To study genetic factors that influence quantitative anti-cyclic citrullinated peptide (anti-CCP) antibody levels in RA patients. METHODS: We carried out a genome wide association study (GWAS) meta-analysis using 1,975 anti-CCP+ RA patients from 3 large cohorts, the Brigham Rheumatoid Art...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cui, Jing, Taylor, Kimberly E., Lee, Yvonne C., Källberg, Henrik, Weinblatt, Michael E., Coblyn, Jonathan S., Klareskog, Lars, Criswell, Lindsey A., Gregersen, Peter K., Shadick, Nancy A., Plenge, Robert M., Karlson, Elizabeth W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948067/
https://ncbi.nlm.nih.gov/pubmed/24385024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2013.68
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