Identification of amino acid-base contacts in the Myc-DNA complex by site-specific bromouracil mediated photocrosslinking.

Myc binds to a 6 bp 2-fold symmetric DNA site: 5'-C-3A-2C-1G+1T+2G+3-3'. Using site-specific 5-bromouracil mediated photocrosslinking, we show that His336 of Myc contacts, or is close to, the thymine 5-methyl group at 2-fold symmetry-related positions -2 and +2 of the DNA site in the Myc-D...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Dong, Q, Blatter, E E, Ebright, Y W, Bister, K, Ebright, R H
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1994
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC394793/
https://ncbi.nlm.nih.gov/pubmed/8306962
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk