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High density micromass cultures of a human chondrocyte cell line: A reliable assay system to reveal the modulatory functions of pharmacological agents

Osteoarthritis is a highly prevalent and disabling disease for which we do not have a cure. The identification of suitable molecular targets is hindered by the lack of standardized, reproducible and convenient screening assays. Following extensive comparisons of a number of chondrocytic cell lines,...

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Detalhes bibliográficos
Main Authors: Greco, K.V., Iqbal, A.J., Rattazzi, L., Nalesso, G., Moradi-Bidhendi, N., Moore, A.R., Goldring, M.B., Dell’Accio, F., Perretti, M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947852/
https://ncbi.nlm.nih.gov/pubmed/21946086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.09.009
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