3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents

The emergence of multidrug-resistant bacteria has created an urgent need for antibiotics with a novel mechanism of action. The bacterial cell division protein FtsZ is an attractive target for the development of novel antibiotics. The benzo[c]phenanthridinium sanguinarine and the dibenzo[a,g]quinoliz...

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Bibliographic Details
Main Authors: Kelley, Cody, Zhang, Yongzheng, Parhi, Ajit, Kaul, Malvika, Pilch, Daniel S., LaVoie, Edmond J.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947851/
https://ncbi.nlm.nih.gov/pubmed/23127490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.10.009
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