FC-98 Regulates TLR9-Mediated of CXCL-10 Expression in Dendritic Cells via MAPK and STAT1 Signaling Pathway

Dendritic cells (DCs), as the most potent professional antigen presenting cells, play a crucial role in both innate and adaptive immune systems. Genomic bacterial DNA mimicked by unmethylated CpG motifs is discovered to possess immunostimulatory effects. CpG-DNA recognized by Toll-like receptor 9 (T...

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Bibliographische Detailangaben
Hauptverfasser: Yang, Yonghong, Dou, Huan, Li, Xiaoqin, Song, Yuxian, Gong, Wei, Tan, Renxiang, Hou, Yayi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947834/
https://ncbi.nlm.nih.gov/pubmed/24696007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/926130
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