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An ER protein functionally couples neutral lipid metabolism on lipid droplets to membrane lipid synthesis in the ER

Eukaryotic cells store neutral lipids, such as triacylglycerol (TAG), in lipid droplets (LDs). Here, we have addressed how LDs are functionally linked to the endoplasmic reticulum (ER). We show in S. cerevisiae that LD growth is sustained by LD-localized enzymes. When LDs grow in early stationary ph...

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Detalhes bibliográficos
Main Authors: Markgraf, Daniel F., Klemm, Robin W., Junker, Mirco, Hannibal-Bach, Hans K., Ejsing, Christer S., Rapoport, Tom A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947819/
https://ncbi.nlm.nih.gov/pubmed/24373967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.11.046
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