ESET histone methyltransferase regulates osteoblastic differentiation of mesenchymal stem cells during postnatal bone development

To investigate the effects of histone methyltransferase ESET (also known as SETDB1) on bone metabolism, we analyzed osteoblasts and osteoclasts in ESET knockout animals, and performed osteogenesis assays using ESET-null mesenchymal stem cells. We found that ESET deletion severely impairs osteoblast...

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Detalhes bibliográficos
Main Authors: Lawson, Kevin A., Teteak, Colin J., Gao, Jidi, Li, Ning, Hacquebord, Jacques, Ghatan, Andrew, Zielinska-Kwiatkowska, Anna, Song, Guangchun, Chansky, Howard A., Yang, Liu
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947621/
https://ncbi.nlm.nih.gov/pubmed/24188826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2013.10.028
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