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Induction of innate and adaptive immunity by delivery of poly dA:dT to dendritic cells
Targeted delivery of antigens to dendritic cells (DCs) is a promising vaccination strategy. However, to ensure immunity, the approach depends on coadministration of an adjuvant. Here we ask whether targeting of both adjuvant and antigen to DCs is sufficient to induce immunity. Using a protein ligati...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3947612/ https://ncbi.nlm.nih.gov/pubmed/23416331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1186 |
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