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Induction of innate and adaptive immunity by delivery of poly dA:dT to dendritic cells

Targeted delivery of antigens to dendritic cells (DCs) is a promising vaccination strategy. However, to ensure immunity, the approach depends on coadministration of an adjuvant. Here we ask whether targeting of both adjuvant and antigen to DCs is sufficient to induce immunity. Using a protein ligati...

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Sonraí Bibleagrafaíochta
Main Authors: Barbuto, Scott, Idoyaga, Juliana, Vila-Perelló, Miquel, Longhi, Maria P, Breton, Gaëlle, Steinman, Ralph M, Muir, Tom W
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947612/
https://ncbi.nlm.nih.gov/pubmed/23416331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1186
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