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Induction of innate and adaptive immunity by delivery of poly dA:dT to dendritic cells

Targeted delivery of antigens to dendritic cells (DCs) is a promising vaccination strategy. However, to ensure immunity, the approach depends on coadministration of an adjuvant. Here we ask whether targeting of both adjuvant and antigen to DCs is sufficient to induce immunity. Using a protein ligati...

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Bibliografische gegevens
Hoofdauteurs: Barbuto, Scott, Idoyaga, Juliana, Vila-Perelló, Miquel, Longhi, Maria P, Breton, Gaëlle, Steinman, Ralph M, Muir, Tom W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947612/
https://ncbi.nlm.nih.gov/pubmed/23416331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1186
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