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mRNA retroposition in human cells: processed pseudogene formation.

Using a sensitive assay for detection of reverse transcription events, we demonstrate that human HeLa cells can 'retropose', i.e. reverse transcribe and integrate, the mRNA of a naive reporter gene, at a low but detectable frequency. Furthermore, we show that the retroposed copies have all the hallm...

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Udgivet i:EMBO J
Principais autores: Maestre, J, Tchénio, T, Dhellin, O, Heidmann, T
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394758/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8557053/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00324.x
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