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The dimerization/packaging sequence is dispensable for both the formation of high-molecular-weight RNA complexes within retroviral particles and the synthesis of proviruses of normal structure.

Retroviral particles contain a dimer of two genomic RNA molecules, linked by noncovalent intermolecular bonds. Studies by electron microscopy of viral RNA extracted from virions as well as in vitro studies have implicated a sequence, designated the dimer linkage sequence (DLS), in the dimerization p...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Tchénio, T, Heidmann, T
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1995
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188679/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7815486/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.2.1079-1084.1995
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